SYNGR4 AND PLEKHB1 DEREGULATION IN MOTOR NEURONS OF AMYOTROPHIC LATERAL SCLEROSIS MODELS: POTENTIAL CONTRIBUTIONS TO PATHOBIOLOGY

SYNGR4 and PLEKHB1 deregulation in motor neurons of amyotrophic lateral sclerosis models: potential contributions to pathobiology

Amyotrophic lateral sclerosis is the most common adult-onset neurodegenerative disease affecting motor neurons.Its defining feature is progressive loss of motor neuron function in the cortex, brainstem, and spinal cord, leading to paralysis and death.Despite major advances in identifying genes that can cause disease when mutated and model the disea

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Studies on Shell and Tube Heat Exchanger Analysis: A Review

Heat exchanger (HX), a device used for transferring energy in the form of heat among two or more fluids of varying temperatures that are in contact thermally with each other.Most adopted heat transfer devices in industries are Shell and Tube Heat Exchangers (S&T HXs) therefore they are most common in many industrial applications such arm tray for w

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Nonlinear Controllers Based on Exact Feedback Linearization for Series-Compensated DFIG-Based Wind Parks to Mitigate Sub-Synchronous Control Interaction

The increasing penetration of wind power in the grid has driven the integration of wind farms with power systems that are series-compensated to enhance power transfer capability and dynamic stability.This may lead to sub-synchronous control interaction (SSCI) problems in series-compensated doubly-fed induction generator (DFIG)-based wind farms.To m

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Percutaneous tricuspid valve replacement in childhood

Percutaneous replacement of the tricuspid valve with cincinnati reds cake a bovine jugular venous valve (melody valve) was successfully undertaken in a 9-year-old boy.The patient had a previous history of bacterial endocarditis of the native tricuspid valve in infancy.Initially, a pericardial patch valve was created, followed by surgical replacemen

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